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G InformationText S1 A file containing 3 supplementary figures, aderivation of your remedy for KFP applied to a linear metabolic pathway, a discussion on applying (r)KFP to metabolic cycles, the description of an analytical method to studying the effects of removing metabolites and pathways, and effects of pathwayAuthor ContributionsConceived and designed the experiments: LH JWL. Performed the experiments: DK XL. Analyzed the information: LH. Wrote the paper: LH JWL CRM.Just about every year, two million new men and women are diagnosed with N6-Phenylethyladenosine cardiovascular disease worldwide 1. Patients living with that chronic condition, as well as careful monitoring of their well being status, want emotional assistance to cope with challenges really hard to treat. In this context, well being social networks2 are virtual environments exactly where on the net help groups constitute an alternative aimed at generating relationships involving patients with equivalent interests (Figure 1).MethodsBecause this study concentrate on cardiac disease, a systematic critique of the literature was conducted with articles published from 2007 to 2012 and collected from the following databases: PubMed; (ACM) and (IEEE). The search for scientific articles was restricted to these assessing the usage of `health social networks’ by people today with cardiovascular troubles, but no outcome was obtained together with the expression `health social networks’. Thus, the keyword `online support groups’ was utilized.KeywordsCardiovascular Diseases; Social Network; Discussion Forums; Data Solutions; Data Exchange.Mailing Address: Edhelmira Lima Medina Av. Visconde do Rio Branco, 51, Centro. Postal Code 24020-000,Niter , RJ – Brasil E-mail: [email protected], [email protected] Manuscript received December 10, 2012; revised manuscript December 19, 2012; accepted March 14, 2013.DOI: 10.5935/abc.ITU – International Telecommunication Union (report “Trends in Telecommunication Reform”). comScore – http://www.comscore.com/ – specialized in measuring the digital world and digital marketing and advertising intelligence – accessed in October 2012. ACM (Association for Computing Machinery). IEEE (Institute of Electrical and Electronic Engineer) are relevant references in the areas associated to Computing ScienceeMedina et al. Wellness social networksClinical Updateserver World-wide-web Connection DevicesdatabaseBlogs Wikis Comments Messages Social NetworkPatientTimeline InteractionsModeratorFigure 1 General model of a social overall health network.The following terms have been searched: social network; support groups; virtual communities; and on the web patient social network. They had been searched isolated or associated together with the following health PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20178013 descriptors that happen to be a part of the Healthcare Topic Headings (MeSH) vocabulary: heart; cardiac failure; cardiovascular disease; hypertension patients; and well being. Within the PubMed database, the search was performed solely together with the terms `online support groups’ and `health virtual communities’, with no association with other descriptors, mainly because PubMed can be a database on life sciences and biomedical topics. In IEEEXplore, the terms `social network’ and `health online’ have been used for the search. In the ACM database, all descriptors have been searched and related to ensure that the major term, `online support groups’, was combined with all the following wellness descriptors: diseases; medicine; individuals; heart; and wellness. The exclusion criteria comprised articles with incomplete information and facts and articles not connected to cardiovascular diseases.HeartNet site A pioneer study on the.

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