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nesthesia Vaginal delivery Labor epidural CCR2 Inhibitor Formulation analgesia Caesarean section Neuroaxial anesthesia Basic anesthesia Cesarean section indication Obstetric Elective Not specified499 338 (67.7) 147 (29.4) 14 (2.8) 499 10 (two) 395 (79.15) 77 (15.43) 17 (3.four) 499 129 (25.85) 107/129 (83) 370 (74.15) 367/370 (99.two) 3/370 (0.8) 370 174 (47.02) 133 (35.95) 63 (17.03)Conclusions: We did not uncover any substantial association in between heparin dose or the time from final dose to delivery and bleeding or thrombotic complications. There was a higher rate of elective caesarean sections. The education in the pregnant woman for the optimal time for you to hold heparin prior to delivery is usually a safe approach without considerably increasing the risk of hemorrhagic or thrombotic complications. L. Perucci1; K. Pinto1; S. Silva1; E. Lage2; P. Teixeira2; A. Barbosa2; P. Alpoim2; L. Sousa2; L. Dusse2; A. TalvaniPB1300|Preeclampsia and Inflammatory Lipid Mediators: A Longitudinal StudyFederal University of Ouro Preto, Ouro Preto, Brazil; 2FederalUniversity of Minas Gerais, Belo Horizonte, Brazil Caspase 1 Chemical Source PB1299|New Criteria for Assessing Hemostasis Problems in Pregnant Ladies with Chronic Kidney Disease I. Vasilenko1,2; I. Nikolskaya3; E. Shestero3; V. Metelin1,two; D. KassinaBackground: The levels of pro-inflammatory (e.g. leukotriene B4-LTB4) and pro-resolving (e.g. lipoxin A4-LXA4, and resolvin D1-RvD1) lipid mediators happen to be not too long ago investigated in preeclampsia (PE). Nonetheless, the production of those mediators all through gestation in each healthy and diseased contexts remains unclear. Aims: Investigate LTB4, LXA4, and RvD1 levels throughout gestation in pregnant ladies with threat things for PE who either developed (N = 11) or did not develop (N = 7) the illness. Methods: The ethics committee in the Federal University of Minas Gerais (#0618.0.203.0000) authorized the study protocol and all participants provided written informed consent. LTB4, LXA4 and RvD1 plasma levels were measured by immunoassays at 3 timepoints: 129, 209, and 304 weeks of gestation in both groups. Final results: Table 1 shows patients’ clinical traits.M.F. Vladimirsky Moscow Regional Clinical and Analysis Institute(MONIKI), Moscow, Russian Federation; 2A.N. Kosygin Russian State University, Moscow, Russian Federation; 3Moscow Regional Analysis Institute of Obstetrics and Gynecology (MONIIAG), Moscow, Russian Federation Background: The pregnancy of ladies with kidney disease is followed by elevated frequency of gestational complications development like endotheliosis, inflammation, oxidative tension, and hemostatic impairments. Within this connection, a specific relevance could be the look for objective and informative criteria for blood clotting disorders in pregnant ladies. Aims: The aim – to make a lot easier the forecasting of attainable complications in mother plus a youngster, evaluation of their situation severity, and therapy efficacy.ABSTRACT961 of|TABLE 1 Clinical traits of your studied pregnant womenParameters Age (years)aPregnant women who did not create PE (N = 17) 27 8 23.6 (23.25.9) 1.0 (1.0.five) 112 11 71 9 114 9 71 4 115 (11020) 70 (708)aPregnant women who created PE (N = 11) 27 4 28.7 (22.51.eight) 2.0 (1.0.0) 119 7 77 8 116 15 78 13 140 (13571) 110 (8915)P 0.598 0.073 0.235 0.271 0.138 0.313 0.072 0.001 0.001BMI at study admission (kg/m2)b Quantity of gestationsb SBP at study admission (mmHg)a DBP at study admission (mmHg) 2nd SBP measurement (mmHg)a 2nd DBP measurement (mmHg)a SBP prior to delivery (mmHg)b DBP b

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