Product Name :
2′-Deoxy-5′-O-DMT-2′-fluorouridine
Description:
2′-Deoxy-5′-O-DMT-2′-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.
CAS:
146954-74-7
Molecular Weight:
548.56
Formula:
C30H29FN2O7
Chemical Name:
1-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-fluoro-4-hydroxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Smiles :
COC1=CC=C(C=C1)C(OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1C=CC(=O)NC1=O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC
InChiKey:
CSSFZSSZXOCCJB-YULOIDQLSA-N
InChi :
InChI=1S/C30H29FN2O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-27(35)26(31)28(40-24)33-17-16-25(34)32-29(33)36/h3-17,24,26-28,35H,18H2,1-2H3,(H,32,34,36)/t24-,26-,27-,28-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Eblasakimab} MedChemExpress|{Eblasakimab} Immunology/Inflammation|{Eblasakimab} Protocol|{Eblasakimab} In Vitro|{Eblasakimab} manufacturer|{Eblasakimab} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{GLP-1 receptor agonist 1} site|{GLP-1 receptor agonist 1} GCGR|{GLP-1 receptor agonist 1} Purity & Documentation|{GLP-1 receptor agonist 1} Formula|{GLP-1 receptor agonist 1} manufacturer|{GLP-1 receptor agonist 1} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:35954127
Additional information:
2′-Deoxy-5′-O-DMT-2′-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.|Product information|CAS Number: 146954-74-7|Molecular Weight: 548.56|Formula: C30H29FN2O7|Chemical Name: 1-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-fluoro-4-hydroxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione|Smiles: COC1=CC=C(C=C1)C(OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1C=CC(=O)NC1=O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC|InChiKey: CSSFZSSZXOCCJB-YULOIDQLSA-N|InChi: InChI=1S/C30H29FN2O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-27(35)26(31)28(40-24)33-17-16-25(34)32-29(33)36/h3-17,24,26-28,35H,18H2,1-2H3,(H,32,34,36)/t24-,26-,27-,28-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|2′-Deoxy-5′-O-DMT-2′-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2′-Deoxy-5′-O-DMT-2′-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM.|Products are for research use only. Not for human use.|
