CeSAX7

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Product Name :
CeSAX7
Clone ID/Product Name: CeSAX7;
Available to For-Profits: Yes;
Alternate Antibody Name: SAX7, 11.2.1;
Gene Symbol: sax-7;
Ab Isotype: MIgG1;
Gene Name: ;
Antibody Registry ID: AB_10567266 ;
Uniprot ID: Q53U86 Q53U87 ;
Entrez Gene ID: 177602 ;
Clonality: Monoclonal;
Immunogen: Recombinant His6-tagged SAX-7 fusion protein;
Immunogen Sequence: Partial protein;
Myeloma Strain: P3X63Ag8.653;
Epitope Mapped: Yes;
Antigen Name: SAX-7;
Epitope Location or Sequence: C-terminal cytoplasmic domain 94 aa;
Alternate Antigen Name: ;
Deposit Date: 2/16/2010;
Antigen Molecular Weight: Predicted: 124 and 145 kDa; Apparent: multiple bands between 45 and 200 kDa;
Antigen Sequence: ;
Depositor Institution: Washington University Medical School;
Antigen Species: C. elegans;
Depositor Notes: Works on C. elegans whole mounts. Stains the plasma membrane at cell-cell contacts. Works poorly in detecting SAX-7 on immunoblots. By western blot, CeSAX7 identifies a band of 55 kDa which may represent a post-translational cleaved product [PMID: 20405020].;
Host Species: mouse;
Hybridoma Cells Available : Yes;
Confirmed Species Reactivity: C. elegans;
Additional Information: SAX-7 is a homolog of the cell adhesion molecule L1/CAM which localizes most prominently to sites of cell-cell contact in the nervous system.;
Predicted Species Reactivity: ;
Human Protein Atlas: ;
Additional Characterization: ;
Recommended Applications: Immunofluorescence, Western Blot;

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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