DCAD2

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Product Name :
DCAD2
Clone ID/Product Name: DCAD2;
Available to For-Profits: Yes;
Alternate Antibody Name: ;
Gene Symbol: shg;
Ab Isotype: RIgG2a, kappa light chain;
Gene Name: ;
Antibody Registry ID: AB_528120 ;
Uniprot ID: Q24298 ;
Entrez Gene ID: 37386 ;
Clonality: Monoclonal;
Immunogen: Proteins co-immunoprecipitated with an anti-alpha-catenin mAb, DCAT-1.;
Immunogen Sequence: Full length protein;
Myeloma Strain: P3-X63-Ag8-U1;
Epitope Mapped: Yes;
Antigen Name: cadherin, DE- ;
Epitope Location or Sequence: Between cadherin repeats 0 and 1;
Alternate Antigen Name: ;
Deposit Date: 1/7/2004;
Antigen Molecular Weight: Predicted: 170 kDa; Apparent: 230 kDa [precursor] and 150 kDa [mature form];
Antigen Sequence: ;
Depositor Institution: Kyoto Univ. Graduate Sch.of Biostudies;
Antigen Species: Drosophila;
Depositor Notes: Suitable for use in immunostaining and immunoprecipitation. In western blot analysis, DCAD1, another rat monoclonal antibody to DE-cadherin, is more sensitive than DCAD2, although DCAD1 is not appropriate for staining. About requests of DCAD1, please contact Tadashi Uemura . Conditions for immunostaining are described in our papers ; in addition please note the following comments. 1/ Fixatives . Either fixation protocol works to stain embryos and discs. To stain cultured cells, only the 4% paraformaldehyde condition worked in our hands. We do not prefer any fix solutions including EDTA or EGTA, because cadherin is easily degraded under Ca++- free conditions. 2/ We suspect that the epitope may be sensitive to long exposure to alcohol. So, embryos stored in alcohol may not be stained. 3/ Photos should be taken under confocal microscope. 4/ HRP/DAB reaction has never given clear-cut signals for DE-cadherin at cell-cell contact sites.;
Host Species: rat;
Hybridoma Cells Available : Yes;
Confirmed Species Reactivity: Drosophila;
Additional Information: ;
Predicted Species Reactivity: ;
Human Protein Atlas: ;
Additional Characterization: ;
Recommended Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot;

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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