DN-Ex #8

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Product Name :
DN-Ex #8
Clone ID/Product Name: DN-Ex #8;
Available to For-Profits: Yes;
Alternate Antibody Name: ;
Gene Symbol: CadN;
Ab Isotype: RIgG2a;
Gene Name: ;
Antibody Registry ID: AB_528121 ;
Uniprot ID: O15943 ;
Entrez Gene ID: 35070 ;
Clonality: Monoclonal;
Immunogen: Recombinant fusion protein containing the extracellular region of N-cadherin from cadherin repeats 2 to 8.;
Immunogen Sequence: Partial protein;
Myeloma Strain: P3-X63-Ag8-U1;
Epitope Mapped: Yes;
Antigen Name: Cadherin, DN- ;
Epitope Location or Sequence: extracellular region including CR2-CR8;
Alternate Antigen Name: ;
Deposit Date: 1/7/2004;
Antigen Molecular Weight: Predicted: 347 kDa; Apparent: 300 and 200 kDa;
Antigen Sequence: ;
Depositor Institution: Kyoto Univ. Graduate Sch.of Biostudies;
Antigen Species: Drosophila;
Depositor Notes: Suitable to use in immunostaining and western blots. 1/ Staining of embryos and discs; both fixative 1 and fixative 2 ) work. 2/ Staining of S2 cells; fixative 1 doesn’t work, use fixative 2. 3/ Staining of pupal or adult heads for light microscope; find details in our MCN paper and references therein such as Uchida et al. and Hoshino et al. . For better fixation, we cut pupal or adult heads into halves. 4? ImmunoEM of adult heads; find details in our MCN paper. We do not add EDTA or EGTA in any fixatives, because cadherins are easily degraded under Ca++- free conditions.;
Host Species: rat;
Hybridoma Cells Available : Yes;
Confirmed Species Reactivity: Drosophila;
Additional Information: Marker of neuropil;
Predicted Species Reactivity: ;
Human Protein Atlas: ;
Additional Characterization: ;
Recommended Applications: Immunofluorescence, Immunohistochemistry, Western Blot;

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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