E1.9

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Product Name :
E1.9
Clone ID/Product Name: E1.9;
Available to For-Profits: Yes;
Alternate Antibody Name: ;
Gene Symbol: ;
Ab Isotype: MIgM;
Gene Name: ;
Antibody Registry ID: AB_531876 ;
Uniprot ID: ;
Entrez Gene ID: ;
Clonality: Monoclonal;
Immunogen: Whole murine cells from the mid- and hindbrain ;
Immunogen Sequence: Full length protein;
Myeloma Strain: FOX-NY;
Epitope Mapped: No;
Antigen Name: neurofilaments, primary sensory and motor neurons;
Epitope Location or Sequence: ;
Alternate Antigen Name: ;
Deposit Date: 10/24/1990;
Antigen Molecular Weight: ;
Antigen Sequence: ;
Depositor Institution: Max Planck Institute for Heart & Lung Research;
Antigen Species: Mouse;
Depositor Notes: filaments in growing primary sensory and motor neurons;
Host Species: mouse;
Hybridoma Cells Available : Yes;
Confirmed Species Reactivity: Human, Mouse, Rat;
Additional Information: In the original paper for E1.9 [PMID: 2300585], the immunogen was described as rat E12, but the subsequent paper from the same authors and in the Depositor’s notes it was described as mouse E11. The E1.9 epitope is developmentally regulated. E1.9 recognizes a cytoplasmic epitope in the primary sensory and motor neurons during axonal outgrowth, appearing at E8.5 and disappearing by E12 in the mouse when the same cell populations become positive for mAb B10. It stains neural crest-derived sensory neurons as well as placode-derived sensory neurons . It is not clear which filaments are recognized by this antibody. For this reason we didn’t link it to a Uniprot or gene ID. See mAb B10 for a related antibody.;
Predicted Species Reactivity: ;
Human Protein Atlas: ;
Additional Characterization: ;
Recommended Applications: Immunofluorescence;

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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