Product Name :
Mcl-1 antagonist 1
Description:
Mcl-1 antagonist 1 is a Mcl-1 protein antagonist extracted from patent WO2019173181, compound 200.
CAS:
2376775-05-0
Molecular Weight:
850.41
Formula:
C41H54ClF2N5O8S
Chemical Name:
(1S,3’R,6’R,7’S,15’R)-6-chloro-7′-[2-(3,3-difluoroazetidin-1-yl)ethoxy]-15′-hydroxy-N-[(2-hydroxyethyl)(methyl)sulfamoyl]-12′-methyl-13′-oxo-3,4-dihydro-2H-20′-oxa-1′,12′-diazaspiro[naphthalene-1,22′-tetracyclo[14.7.2.0³,⁶.0¹⁹,²⁴]pentacosane]-8′,16′,18′,24′-tetraene-15′-carboxamide
Smiles :
CN(CCO)S(=O)(=O)NC(=O)[C@@]1(O)CC(=O)N(C)CCC=C[C@H](OCCN2CC(F)(F)C2)[C@@H]2CC[C@H]2CN2C[C@]3(COC4=CC=C1C=C24)CCCC1=CC(Cl)=CC=C31 |c:20|
InChiKey:
IHYDZFFQPUKFIP-YHOKPAFBSA-N
InChi :
InChI=1S/C41H54ClF2N5O8S/c1-46-15-4-3-7-35(56-19-17-48-25-40(43,44)26-48)32-11-8-29(32)23-49-24-39(14-5-6-28-20-31(42)10-12-33(28)39)27-57-36-13-9-30(21-34(36)49)41(53,22-37(46)51)38(52)45-58(54,55)47(2)16-18-50/h3,7,9-10,12-13,20-21,29,32,35,50,53H,4-6,8,11,14-19,22-27H2,1-2H3,(H,45,52)/b7-3-/t29-,32+,35-,39-,41+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Mcl-1 antagonist 1 is a Mcl-1 protein antagonist extracted from patent WO2019173181, compound 200.|Product information|CAS Number: 2376775-05-0|Molecular Weight: 850.{{Nicorandil} site|{Nicorandil} Membrane Transporter/Ion Channel|{Nicorandil} Purity & Documentation|{Nicorandil} Purity|{Nicorandil} supplier|{Nicorandil} Epigenetic Reader Domain} 41|Formula: C41H54ClF2N5O8S|Chemical Name: (1S,3’R,6’R,7’S,15’R)-6-chloro-7′-[2-(3,3-difluoroazetidin-1-yl)ethoxy]-15′-hydroxy-N-[(2-hydroxyethyl)(methyl)sulfamoyl]-12′-methyl-13′-oxo-3,4-dihydro-2H-20′-oxa-1′,12′-diazaspiro[naphthalene-1,22′-tetracyclo[14.{{Pexidartinib} medchemexpress|{Pexidartinib} Apoptosis|{Pexidartinib} Technical Information|{Pexidartinib} In Vitro|{Pexidartinib} supplier|{Pexidartinib} Autophagy} 7.2.0³,⁶.0¹⁹,²⁴]pentacosane]-8′,16′,18′,24′-tetraene-15′-carboxamide|Smiles: CN(CCO)S(=O)(=O)NC(=O)[C@@]1(O)CC(=O)N(C)CCC=C[C@H](OCCN2CC(F)(F)C2)[C@@H]2CC[C@H]2CN2C[C@]3(COC4=CC=C1C=C24)CCCC1=CC(Cl)=CC=C31 |c:20||InChiKey: IHYDZFFQPUKFIP-YHOKPAFBSA-N|InChi: InChI=1S/C41H54ClF2N5O8S/c1-46-15-4-3-7-35(56-19-17-48-25-40(43,44)26-48)32-11-8-29(32)23-49-24-39(14-5-6-28-20-31(42)10-12-33(28)39)27-57-36-13-9-30(21-34(36)49)41(53,22-37(46)51)38(52)45-58(54,55)47(2)16-18-50/h3,7,9-10,12-13,20-21,29,32,35,50,53H,4-6,8,11,14-19,22-27H2,1-2H3,(H,45,52)/b7-3-/t29-,32+,35-,39-,41+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24367939 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
