EMA-1

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Product Name :
EMA-1
Clone ID/Product Name: EMA-1;
Available to For-Profits: Yes;
Alternate Antibody Name: ;
Gene Symbol: ;
Ab Isotype: MIgM;
Gene Name: ;
Antibody Registry ID: AB_531885 ;
Uniprot ID: ;
Entrez Gene ID: ;
Clonality: Monoclonal;
Immunogen: Nulli SCC1 EC cells ;
Immunogen Sequence: ;
Myeloma Strain: NS-1;
Epitope Mapped: Yes;
Antigen Name: primordial germ cell surface marker ;
Epitope Location or Sequence: EMA-1 recognizes short chain and long chain glycolipids of cell surface glycoproteins specific of primordial germ cells.;
Alternate Antigen Name: ;
Deposit Date: 9/7/1994;
Antigen Molecular Weight: Apparent: +500 kDa;
Antigen Sequence: ;
Depositor Institution: NIH, NIEHS, RTP and Ontario Veterinary College;
Antigen Species: Mouse;
Depositor Notes: This antibody binds specifically to the surface of primordial germ cells and a variety of adult apical epithelium including oviduct and proximal kidney. This antibody also recognizes antigen in olfactory pits and membranous portions of fins in zebrafish PMID: 19302835.;
Host Species: mouse;
Hybridoma Cells Available : No;
Confirmed Species Reactivity: Amphibian, Avian, Broad species, Fish, Mammal, Zebrafish;
Additional Information: This antibody was originally described and characterized in [Hahnel, A.C., and Eddy, E.M. . Cell surface markers of mouse primordial germ cells defined by two monoclonal antibodies. Gamete Research 15, 25-34]. RRID:AB_531885;
Predicted Species Reactivity: ;
Human Protein Atlas: ;
Additional Characterization: ;
Recommended Applications: FACS, FFPE, Immunofluorescence, Immunohistochemistry, Western Blot;

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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