Product Name :
cis-ACPD
Description:
cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. cis-ACPD is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively.
CAS:
477331-06-9
Molecular Weight:
173.17
Formula:
C7H11NO4
Chemical Name:
(1R, 3R)-1-aminocyclopentane-1, 3-dicarboxylic acid
Smiles :
N[C@]1(C[C@@H](CC1)C(O)=O)C(O)=O
InChiKey:
YFYNOWXBIBKGHB-CLZZGJSISA-N
InChi :
InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. cis-ACPD is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively.|Product information|CAS Number: 477331-06-9|Molecular Weight: 173.17|Formula: C7H11NO4|Chemical Name: (1R, 3R)-1-aminocyclopentane-1, 3-dicarboxylic acid|Smiles: N[C@]1(C[C@@H](CC1)C(O)=O)C(O)=O|InChiKey: YFYNOWXBIBKGHB-CLZZGJSISA-N|InChi: InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{BHQ-880} MedChemExpress|{BHQ-880} Epigenetics|{BHQ-880} Biological Activity|{BHQ-880} Formula|{BHQ-880} custom synthesis} |Shelf Life: ≥12 months if stored properly.{{Omidenepag isopropyl} medchemexpress|{Omidenepag isopropyl} Prostaglandin Receptor|{Omidenepag isopropyl} Protocol|{Omidenepag isopropyl} References|{Omidenepag isopropyl} manufacturer|{Omidenepag isopropyl} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24957087 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|cis-ACPD is a selective group II mGluR agonist, with EC50s of 13, 50, >300 and >300 μM for mGluR2, mGluR4, mGluR1 and mGluR5, respectively. cis-ACPD (1-1000 µM; 60 min) stimulates hydrolysis of 3H-phosphoinositide.|In Vivo:|cis-ACPD (1-1000 mg/kg; i.p.) produces dose-related convulsions in rats.|Products are for research use only. Not for human use.|