Product Name :
Milbemycin oxime
Description:
Milbemycin oxime is a macrocyclic lactone and has broad-spectrum anti-parasitic activity. Milbemycin oxime is composed of milbemycins A4 and A3. Milbemycin oxime binds glutamate-gated chloride channels. Milbemycin oxime is against intestinal nematodes, pulmonary and cardiac helminths.
CAS:
129496-10-2
Molecular Weight:
1097.38
Formula:
C63H88N2O14
Chemical Name:
(1’R,2R,4’S,5S,6R,8’R,13’R,20’R,21’Z,24’S)-24′-hydroxy-21′-(hydroxyimino)-5,6,11′,13′,22′-pentamethyl-3′,7′,19′-trioxaspiro[oxane-2,6′-tetracyclo[15.6.1.1⁴,⁸.0²⁰,²⁴]pentacosane]-10′,14′,16′,22′-tetraen-2′-one; (1’R,2R,4’S,5S,6R,8’R,13’R,20’R,21’Z,24’S)-6-ethyl-24′-hydroxy-21′-(hydroxyimino)-5,11′,13′,22′-tetramethyl-3′,7′,19′-trioxaspiro[oxane-2,6′-tetracyclo[15.6.1.1⁴,⁸.0²⁰,²⁴]pentacosane]-10′,14′,16′,22′-tetraen-2′-one
Smiles :
CC[C@H]1O[C@@]2(C[C@@H]3C[C@@H](CC=C(C)C[C@@H](C)C=CC=C4CO[C@@H]5/C(=N\O)/C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)CC[C@@H]1C.C[C@H]1CC[C@]2(C[C@@H]3C[C@@H](CC=C(C)C[C@@H](C)C=CC=C4CO[C@@H]5/C(=N\O)/C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)O[C@@H]1C |c:10,18,54,62,t:16,60|
InChiKey:
CKVMAPHTVCTEMM-MSWRLCKUSA-N
InChi :
InChI=1S/C32H45NO7.C31H43NO7/c1-6-27-21(4)12-13-31(40-27)17-25-16-24(39-31)11-10-20(3)14-19(2)8-7-9-23-18-37-29-28(33-36)22(5)15-26(30(34)38-25)32(23,29)35;1-18-7-6-8-23-17-36-28-27(32-35)21(4)14-26(31(23,28)34)29(33)37-25-15-24(10-9-19(2)13-18)39-30(16-25)12-11-20(3)22(5)38-30/h7-10,15,19,21,24-27,29,35-36H,6,11-14,16-18H2,1-5H3;6-9,14,18,20,22,24-26,28,34-35H,10-13,15-17H2,1-5H3/b8-7-,20-10-,23-9-,33-28-;7-6-,19-9-,23-8-,32-27-/t19-,21-,24+,25-,26-,27+,29+,31+,32+;18-,20-,22+,24+,25-,26-,28+,30-,31+/m00/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Irinotecan} MedChemExpress|{Irinotecan} Autophagy|{Irinotecan} Purity & Documentation|{Irinotecan} In stock|{Irinotecan} supplier|{Irinotecan} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Meglumine} web|{Meglumine} {Biochemical Assay Reagents}|{Meglumine} Technical Information|{Meglumine} In Vivo|{Meglumine} custom synthesis|{Meglumine} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23805407
Additional information:
Milbemycin oxime is a macrocyclic lactone and has broad-spectrum anti-parasitic activity. Milbemycin oxime is composed of milbemycins A4 and A3. Milbemycin oxime binds glutamate-gated chloride channels. Milbemycin oxime is against intestinal nematodes, pulmonary and cardiac helminths.|Product information|CAS Number: 129496-10-2|Molecular Weight: 1097.38|Formula: C63H88N2O14|Chemical Name: (1’R,2R,4’S,5S,6R,8’R,13’R,20’R,21’Z,24’S)-24′-hydroxy-21′-(hydroxyimino)-5,6,11′,13′,22′-pentamethyl-3′,7′,19′-trioxaspiro[oxane-2,6′-tetracyclo[15.6.1.1⁴,⁸.0²⁰,²⁴]pentacosane]-10′,14′,16′,22′-tetraen-2′-one; (1’R,2R,4’S,5S,6R,8’R,13’R,20’R,21’Z,24’S)-6-ethyl-24′-hydroxy-21′-(hydroxyimino)-5,11′,13′,22′-tetramethyl-3′,7′,19′-trioxaspiro[oxane-2,6′-tetracyclo[15.6.1.1⁴,⁸.0²⁰,²⁴]pentacosane]-10′,14′,16′,22′-tetraen-2′-one|Smiles: CC[C@H]1O[C@@]2(C[C@@H]3C[C@@H](CC=C(C)C[C@@H](C)C=CC=C4CO[C@@H]5/C(=N\O)/C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)CC[C@@H]1C.C[C@H]1CC[C@]2(C[C@@H]3C[C@@H](CC=C(C)C[C@@H](C)C=CC=C4CO[C@@H]5/C(=N\O)/C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)O[C@@H]1C |c:10,18,54,62,t:16,60||InChiKey: CKVMAPHTVCTEMM-MSWRLCKUSA-N|InChi: InChI=1S/C32H45NO7.C31H43NO7/c1-6-27-21(4)12-13-31(40-27)17-25-16-24(39-31)11-10-20(3)14-19(2)8-7-9-23-18-37-29-28(33-36)22(5)15-26(30(34)38-25)32(23,29)35;1-18-7-6-8-23-17-36-28-27(32-35)21(4)14-26(31(23,28)34)29(33)37-25-15-24(10-9-19(2)13-18)39-30(16-25)12-11-20(3)22(5)38-30/h7-10,15,19,21,24-27,29,35-36H,6,11-14,16-18H2,1-5H3;6-9,14,18,20,22,24-26,28,34-35H,10-13,15-17H2,1-5H3/b8-7-,20-10-,23-9-,33-28-;7-6-,19-9-,23-8-,32-27-/t19-,21-,24+,25-,26-,27+,29+,31+,32+;18-,20-,22+,24+,25-,26-,28+,30-,31+/m00/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (91.13 mM). H2O : 1 mg/mL (0.91 mM; ultrasonic and warming and heat to 80°C).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
