Product Name :
Garcinone D
Description:
Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners.
CAS:
107390-08-9
Molecular Weight:
428.47
Formula:
C24H28O7
Chemical Name:
1, 3, 6-trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
Smiles :
CC(C)=CCC1=C(O)C2C(=O)C3=C(CCC(C)(C)O)C(OC)=C(O)C=C3OC=2C=C1O
InChiKey:
TYALNCRUIKOKGP-UHFFFAOYSA-N
InChi :
InChI=1S/C24H28O7/c1-12(2)6-7-13-15(25)10-18-20(21(13)27)22(28)19-14(8-9-24(3,4)29)23(30-5)16(26)11-17(19)31-18/h6,10-11,25-27,29H,7-9H2,1-5H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.{{Charybdotoxin} web|{Charybdotoxin} Membrane Transporter/Ion Channel|{Charybdotoxin} Immunology/Inflammation|{Charybdotoxin} Technical Information|{Charybdotoxin} In Vivo|{Charybdotoxin} custom synthesis} 2 neural stem cell.{{Atosiban} MedChemExpress|{Atosiban} Antagonist|{Atosiban} Immunology/Inflammation|{Atosiban} Protocol|{Atosiban} References|{Atosiban} custom synthesis} Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners.PMID:32538225 |Product information|CAS Number: 107390-08-9|Molecular Weight: 428.47|Formula: C24H28O7|Chemical Name: 1, 3, 6-trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methylbut-2-en-1-yl)-9H-xanthen-9-one|Smiles: CC(C)=CCC1=C(O)C2C(=O)C3=C(CCC(C)(C)O)C(OC)=C(O)C=C3OC=2C=C1O|InChiKey: TYALNCRUIKOKGP-UHFFFAOYSA-N|InChi: InChI=1S/C24H28O7/c1-12(2)6-7-13-15(25)10-18-20(21(13)27)22(28)19-14(8-9-24(3,4)29)23(30-5)16(26)11-17(19)31-18/h6,10-11,25-27,29H,7-9H2,1-5H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Yang X, et al. Garcinone D, a natural xanthone promotes C17.2 neural stem cell proliferation: Possible involvement of STAT3/Cyclin D1 pathway and Nrf2/HO-1 pathway. Neurosci Lett. 2016 Jul 28;626:6-12.Products are for research use only. Not for human use.|
