Product Name :
FTI-277
Description:
FTI-277 is a ras CAAX (C – Cys; A – aliphatic amino acid; X – Ser or Met) peptidomimetic that inhibits farnesyltransferase and blocks Ras oncogenic signaling by accumulating Ras/Raf complexes in the cytoplasm.
CAS:
170006-73-2
Molecular Weight:
447.61
Formula:
C22H29N3O3S2
Chemical Name:
methyl (2S)-2-[(5-[(2R)-2-amino-3-sulfanylpropyl]amino-[1,1′-biphenyl]-2-yl)formamido]-4-(methylsulfanyl)butanoate
Smiles :
COC(=O)[C@H](CCSC)NC(=O)C1=CC=C(C=C1C1C=CC=CC=1)NC[C@@H](N)CS
InChiKey:
GKFPROVOIQKYTO-UZLBHIALSA-N
InChi :
InChI=1S/C22H29N3O3S2/c1-28-22(27)20(10-11-30-2)25-21(26)18-9-8-17(24-13-16(23)14-29)12-19(18)15-6-4-3-5-7-15/h3-9,12,16,20,24,29H,10-11,13-14,23H2,1-2H3,(H,25,26)/t16-,20+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
FTI-277 is a ras CAAX (C – Cys; A – aliphatic amino acid; X – Ser or Met) peptidomimetic that inhibits farnesyltransferase and blocks Ras oncogenic signaling by accumulating Ras/Raf complexes in the cytoplasm.|Product information|CAS Number: 170006-73-2|Molecular Weight: 447.61|Formula: C22H29N3O3S2|Chemical Name: methyl (2S)-2-[(5-[(2R)-2-amino-3-sulfanylpropyl]amino-[1,1′-biphenyl]-2-yl)formamido]-4-(methylsulfanyl)butanoate|Smiles: COC(=O)[C@H](CCSC)NC(=O)C1=CC=C(C=C1C1C=CC=CC=1)NC[C@@H](N)CS|InChiKey: GKFPROVOIQKYTO-UZLBHIALSA-N|InChi: InChI=1S/C22H29N3O3S2/c1-28-22(27)20(10-11-30-2)25-21(26)18-9-8-17(24-13-16(23)14-29)12-19(18)15-6-4-3-5-7-15/h3-9,12,16,20,24,29H,10-11,13-14,23H2,1-2H3,(H,25,26)/t16-,20+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.ERK1/2 inhibitor 2 In Vitro |Shelf Life: ≥12 months if stored properly.Lurtotecan manufacturer |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33000693 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
