Product Name :
Dipotassium glycyrrhizinate
Description:
Dipotassium glycyrrhizinate is a natural compound, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity.
CAS:
68797-35-3
Molecular Weight:
899.11
Formula:
C42H60K2O16
Chemical Name:
(2S,3S,4S,5R,6S)-6-[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-4a,12a,14a-trihydrogenio-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-11-[(potassiooxy)carbonyl]-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy-6-hydrogenio-5-[(2R,3R,4S,5S,6S)-2-hydrogenio-3,4,5-trihydroxy-6-[(potassiooxy)carbonyl]oxan-2-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid
Smiles :
[K+].[K+].CC1(C)[C@@H]2CC[C@]3(C)[C@H](C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C([O-])=O)[C@@]2(C)CC[C@@H]1O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C([O-])=O)C(O)=O
InChiKey:
BIVBRWYINDPWKA-VLQRKCJKSA-L
InChi :
InChI=1S/C42H62O16.2K/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);;/q;2*+1/p-2/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+;;/m0../s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Dipotassium glycyrrhizinate is a natural compound, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity.|Product information|CAS Number: 68797-35-3|Molecular Weight: 899.11|Formula: C42H60K2O16|Synonym:|Glycyrrhizic acid dipotassium|Dipotassium glycyrrhizate|Chemical Name: (2S,3S,4S,5R,6S)-6-[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-4a,12a,14a-trihydrogenio-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-11-[(potassiooxy)carbonyl]-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy-6-hydrogenio-5-[(2R,3R,4S,5S,6S)-2-hydrogenio-3,4,5-trihydroxy-6-[(potassiooxy)carbonyl]oxan-2-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid|Smiles: [K+].Cefotaxime sodium salt MedChemExpress [K+].Oleic acid Na+/K+ ATPase CC1(C)[C@@H]2CC[C@]3(C)[C@H](C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C([O-])=O)[C@@]2(C)CC[C@@H]1O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C([O-])=O)C(O)=O|InChiKey: BIVBRWYINDPWKA-VLQRKCJKSA-L|InChi: InChI=1S/C42H62O16.PMID:32502370 2K/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);;/q;2*+1/p-2/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+;;/m0../s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 5 mg/mL (5.56 mM; Need ultrasonic). H2O : 50 mg/mL (55.61 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Lee SH, et al. Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model. Arch Dermatol Res. 2019 Mar;311(2):131-140.Products are for research use only. Not for human use.|
