Product Name :
Bilirubin
Description:
Bilirubin is a yellow breakdown product of heme catabolism. Bilirubin exhibits antioxidant and antimutagenic effects.
CAS:
635-65-4
Molecular Weight:
584.66
Formula:
C33H36N4O6
Chemical Name:
3-(2-[3-(2-carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl-5-[(4-ethenyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl)propanoic acid
Smiles :
CC1=C(C=C)C(=O)NC1=CC1NC(CC2NC(C=C3NC(=O)C(C)=C3C=C)=C(C)C=2CCC(O)=O)=C(CCC(O)=O)C=1C
InChiKey:
BPYKTIZUTYGOLE-IFADSCNNSA-N
InChi :
InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bilirubin is a yellow breakdown product of heme catabolism. Bilirubin exhibits antioxidant and antimutagenic effects.|Product information|CAS Number: 635-65-4|Molecular Weight: 584.66|Formula: C33H36N4O6|Chemical Name: 3-(2-[3-(2-carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl-5-[(4-ethenyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl)propanoic acid|Smiles: CC1=C(C=C)C(=O)NC1=CC1NC(CC2NC(C=C3NC(=O)C(C)=C3C=C)=C(C)C=2CCC(O)=O)=C(CCC(O)=O)C=1C|InChiKey: BPYKTIZUTYGOLE-IFADSCNNSA-N|InChi: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 6 mg/mL (10.26 mM; Need ultrasonic). H2O : 1 mg/mL (1.71 mM; ultrasonic and adjust pH to 11 with NaOH).Laquinimod Biological Activity |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Diclofenac COX |Shelf Life: ≥12 months if stored properly.PMID:33198515 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Unconjugated Bilirubin inhibits the cleavage of F485-rVWF73-H, D633-rVWF73-H, and GST-rVWF71-11K by ADAMTS13 in a concentration-dependent manner with a half-maximal inhibitory concentration (IC50) of ~13 μM, ~70 μM, and ~17 μM, respectively. Unconjugated Bilirubin also dose-dependently inhibits the cleavage of multimeric VWF by ADAMTS13 under denaturing conditions. Bilirubin exhibits antioxidant and antimutagenic effects in vitro.|Products are for research use only. Not for human use.|
