Product Name :
Rabbit anti-KCNA3 Polyclonal Antibody(Center)
Synonym :
Potassium voltage-gated channel subfamily A member 3; HGK5; HLK3; HPCN3; Voltage-gated K(+) channel HuKIII; Voltage-gated potassium channel subunit Kv13; KCNA3
Host :
Rabbit
Species Reactivity:
Human
Specificity :
This KCNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3.
Predicted Reactivity:
Mouse, Rat
Applications :
WB~~1:1000
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Signal Transduction
Background :
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
UniProt :
P22001
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |Synonym Potassium voltage-gated channel subfamily A member 3; HGK5; HLK3; HPCN3; Voltage-gated K(+) channel HuKIII; Voltage-gated potassium channel subunit Kv13; KCNA3 |Host Rabbit |Specificity This KCNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3. |Species Reactivity Human |Predicted Reactivity Mouse, Rat |Applications WB~~1:1000 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Signal Transduction |Target |Background Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. |Cellular localization Cell membrane; Multi-pass membrane protein |UniProt P22001 |References |References Wang, T., et al. J. Neurosci. 30(14):5020-5027(2010)Tu, L.W., et al. J. Mol. Biol. 396(5):1346-1360(2010)Poulopoulou, C., et al. Neurobiol. Dis. 37(2):339-348(2010)Nicolaou, S.A., et al. Cell Calcium 47(1):19-28(2010)Feng, D.Y., et al. Zhonghua Xin Xue Guan Bing Za Zhi 37(7):599-604(2009) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-KCNA3 Polyclonal Antibody(Center)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
2636846-41-6 manufacturer 477775-14-7 Formula PMID:25905218 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
