Product Name :
IKK 16
Description:
IKK-16 is a potent and slective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). KK-16 inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells.
CAS:
873225-46-8
Molecular Weight:
483.63
Formula:
C28H29N5OS
Chemical Name:
4-(1-benzothiophen-2-yl)-N-{4-[4-(pyrrolidin-1-yl)piperidine-1-carbonyl]phenyl}pyrimidin-2-amine
Smiles :
O=C(C1C=CC(=CC=1)NC1=NC(=CC=N1)C1=CC2=CC=CC=C2S1)N1CCC(CC1)N1CCCC1
InChiKey:
BWZJBXAPRCVCKQ-UHFFFAOYSA-N
InChi :
InChI=1S/C28H29N5OS/c34-27(33-17-12-23(13-18-33)32-15-3-4-16-32)20-7-9-22(10-8-20)30-28-29-14-11-24(31-28)26-19-21-5-1-2-6-25(21)35-26/h1-2,5-11,14,19,23H,3-4,12-13,15-18H2,(H,29,30,31)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Alogliptin} web|{Alogliptin} Dipeptidyl Peptidase|{Alogliptin} Technical Information|{Alogliptin} Data Sheet|{Alogliptin} custom synthesis|{Alogliptin} Cancer}
Shelf Life:
≥360 days if stored properly.{{Peramivir} site|{Peramivir} Stem Cell/Wnt|{Peramivir} Protocol|{Peramivir} In Vitro|{Peramivir} custom synthesis|{Peramivir} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24103058
Additional information:
IKK-16 is a potent and slective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). KK-16 inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells.|Product information|CAS Number: 873225-46-8|Molecular Weight: 483.63|Formula: C28H29N5OS|Chemical Name: 4-(1-benzothiophen-2-yl)-N-{4-[4-(pyrrolidin-1-yl)piperidine-1-carbonyl]phenyl}pyrimidin-2-amine|Smiles: O=C(C1C=CC(=CC=1)NC1=NC(=CC=N1)C1=CC2=CC=CC=C2S1)N1CCC(CC1)N1CCCC1|InChiKey: BWZJBXAPRCVCKQ-UHFFFAOYSA-N|InChi: InChI=1S/C28H29N5OS/c34-27(33-17-12-23(13-18-33)32-15-3-4-16-32)20-7-9-22(10-8-20)30-28-29-14-11-24(31-28)26-19-21-5-1-2-6-25(21)35-26/h1-2,5-11,14,19,23H,3-4,12-13,15-18H2,(H,29,30,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
