H4B4

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Product Name :
H4B4
Clone ID/Product Name: H4B4;
Available to For-Profits: Yes;
Alternate Antibody Name: CD107b;
Gene Symbol: LAMP2;
Ab Isotype: MIgG1;
Gene Name: ;
Antibody Registry ID: AB_528129 ;
Uniprot ID: P13473 ;
Entrez Gene ID: 3920 ;
Clonality: Monoclonal;
Immunogen: Human adherent peripheral blood cells;
Immunogen Sequence: Full length protein;
Myeloma Strain: P3X653-Ag8;
Epitope Mapped: Yes;
Antigen Name: LAMP-2 ;
Epitope Location or Sequence: Luminal region of LAMP-2;
Alternate Antigen Name: ;
Deposit Date: 4/12/1993;
Antigen Molecular Weight: Predicted: 42 kDa; Apparent: 120 kDa;
Antigen Sequence: ;
Depositor Institution: Johns Hopkins University School of Medicine;
Antigen Species: Human;
Depositor Notes: Fusion: 1983;
Host Species: mouse;
Hybridoma Cells Available : No;
Confirmed Species Reactivity: Human;
Additional Information: LAMP2 is a marker of lysosmes and late endosomes. H4B4 has been reported to recognize all three LAMP-2 isoforms A, B, and C [PMID: 22365987], suggesting that the epitope is located on the luminal region of LAMP-2 common to all isoforms. This antibody induces apoptosis of human microvascular endothelium in vitro [PMID: 18836458]. RRID:AB_528129;
Predicted Species Reactivity: ;
Human Protein Atlas: ;
Additional Characterization: ;
Recommended Applications: FACS, Function Blocking, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot;

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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