Product Name :
Amino-PEG6-alcohol
Description:
Amino-PEG6-alcohol is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG6-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
39160-70-8
Molecular Weight:
281.35
Formula:
C12H27NO6
Chemical Name:
17-amino-3,6,9,12,15-pentaoxaheptadecan-1-ol
Smiles :
NCCOCCOCCOCCOCCOCCO
InChiKey:
ICUIZKMGHRMMDZ-UHFFFAOYSA-N
InChi :
InChI=1S/C12H27NO6/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h14H,1-13H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Amino-PEG6-alcohol is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG6-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 39160-70-8|Molecular Weight: 281.35|Formula: C12H27NO6|Chemical Name: 17-amino-3,6,9,12,15-pentaoxaheptadecan-1-ol|Smiles: NCCOCCOCCOCCOCCOCCO|InChiKey: ICUIZKMGHRMMDZ-UHFFFAOYSA-N|InChi: InChI=1S/C12H27NO6/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h14H,1-13H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Asundexian} site|{Asundexian} Metabolic Enzyme/Protease|{Asundexian} Technical Information|{Asundexian} Data Sheet|{Asundexian} custom synthesis|{Asundexian} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Obiltoxaximab} site|{Obiltoxaximab} Bacterial|{Obiltoxaximab} Purity & Documentation|{Obiltoxaximab} References|{Obiltoxaximab} custom synthesis|{Obiltoxaximab} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33232014 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
