Cy–exist between these studies. The LURN is conducting a 1-year prospective

Cy–exist between these studies. The LURN is conducting a 1-year prospective observational cohort study and associated sub-studies to identify important patient sub-types and improve upon symptom measurement for LUTD through development of new questionnaires centered on patient experience. A future goal is to develop and disseminate new research tools and other resources to the community. The PLUS Research Consortium was initiated in 2015 as an effort to establish an evidence base for normal (healthy) bladder function, including behavioral and other risk factors for symptoms of bladder infection, urinary incontinence, voiding dysfunction, overactive bladder, and IC/BPS in women over a wide age range that will provide the foundation for future prevention studies. These research programs have already developed linesof collaboration in their study of complementary urologic conditions and patient groups. This includes sharing best AZD3759 web practice guidelines to promote similar approaches to biosample and data collection; adopting common CI-1011MedChemExpress Avasimibe neuroimaging methodologies and a common neuroimaging core, specifically for the MAPP Research Network and the LURN; and developing a common strategy to disseminate key findings to patients, the community, and practicing clinicians; among others. As the LURN and PLUS develop their datasets and resulting insights, comparative analysis between these three studies will provide unprecedented opportunities for a more global understanding of bladder and LUTD and symptoms across disorders, including IC/BPS. The growing interest in the relationships between chronic pain conditions often found in association in patients has motivated the National Institutes of Health (NIH) Pain Consortium (http://painconsortium.nih. gov/), a group established to enhance pain research and collaboration across NIH Institutes and Centers, to better integrate existing and future data from relevant clinical studies and data resources and enhance future collaborations through development of common data collection strategies and phenotyping tools. In support of this goal, the NIH Pain Consortium convened the 2014 Investigator’s Meeting on Chronic Overlapping Pain Conditions in which investigators from numerous large-cohort studies and research resource projects discussed how to leverage these efforts. Groups represented included the MAPP Research Network; the Collaborative Health Outcomes Information Registry (CHOIR) (http://snapl.stanford.edu/choir/), a collaborative partnership between the NIH and Stanford University to provide an open source platform for outcomes data from chronic pain patients, including IC/BPS; the National Center for Biotechnology Information (NCBI) Database of Genotypes and Phenotypes (dbGaP) (http:// www.ncbi.nlm.nih.gov/gap), which serves to archive and distribute results of genome-wide association studies, medical sequencing, molecular diagnostic assays, as well as association between genotype and non-clinical traits and extends well beyond urologic or chronic pain disorders; and the National Institute of Dental and Craniofacial Research’s (NIDCR) Orofacial Pain Prospective Evaluation and Risk Assessment (OPPERA) Study (53) (www.oppera.org), launched in 2005 as a groundbreaking prospective study to identify the biological, psychological, and genetic risk factors for first onset and chronic temporomandibular joint and muscle disorders (TMDs); among others. Numerous recommendations were developed by?Translational Andrology a.Cy–exist between these studies. The LURN is conducting a 1-year prospective observational cohort study and associated sub-studies to identify important patient sub-types and improve upon symptom measurement for LUTD through development of new questionnaires centered on patient experience. A future goal is to develop and disseminate new research tools and other resources to the community. The PLUS Research Consortium was initiated in 2015 as an effort to establish an evidence base for normal (healthy) bladder function, including behavioral and other risk factors for symptoms of bladder infection, urinary incontinence, voiding dysfunction, overactive bladder, and IC/BPS in women over a wide age range that will provide the foundation for future prevention studies. These research programs have already developed linesof collaboration in their study of complementary urologic conditions and patient groups. This includes sharing best practice guidelines to promote similar approaches to biosample and data collection; adopting common neuroimaging methodologies and a common neuroimaging core, specifically for the MAPP Research Network and the LURN; and developing a common strategy to disseminate key findings to patients, the community, and practicing clinicians; among others. As the LURN and PLUS develop their datasets and resulting insights, comparative analysis between these three studies will provide unprecedented opportunities for a more global understanding of bladder and LUTD and symptoms across disorders, including IC/BPS. The growing interest in the relationships between chronic pain conditions often found in association in patients has motivated the National Institutes of Health (NIH) Pain Consortium (http://painconsortium.nih. gov/), a group established to enhance pain research and collaboration across NIH Institutes and Centers, to better integrate existing and future data from relevant clinical studies and data resources and enhance future collaborations through development of common data collection strategies and phenotyping tools. In support of this goal, the NIH Pain Consortium convened the 2014 Investigator’s Meeting on Chronic Overlapping Pain Conditions in which investigators from numerous large-cohort studies and research resource projects discussed how to leverage these efforts. Groups represented included the MAPP Research Network; the Collaborative Health Outcomes Information Registry (CHOIR) (http://snapl.stanford.edu/choir/), a collaborative partnership between the NIH and Stanford University to provide an open source platform for outcomes data from chronic pain patients, including IC/BPS; the National Center for Biotechnology Information (NCBI) Database of Genotypes and Phenotypes (dbGaP) (http:// www.ncbi.nlm.nih.gov/gap), which serves to archive and distribute results of genome-wide association studies, medical sequencing, molecular diagnostic assays, as well as association between genotype and non-clinical traits and extends well beyond urologic or chronic pain disorders; and the National Institute of Dental and Craniofacial Research’s (NIDCR) Orofacial Pain Prospective Evaluation and Risk Assessment (OPPERA) Study (53) (www.oppera.org), launched in 2005 as a groundbreaking prospective study to identify the biological, psychological, and genetic risk factors for first onset and chronic temporomandibular joint and muscle disorders (TMDs); among others. Numerous recommendations were developed by?Translational Andrology a.